Thursday, March 18, 2010

why immune cel not attack the new latctating breast acc to danger hypo and query on this

Why immune cel not attack the new latctating breast acc to danger hypo and query on this

To xplain why new lactating breast is not rejected matzinger's hypo assert the following:-

“ Why do mammalian mothers not reject their fetuses or attack their

newly lactating breasts, which produce milk proteins that were not part of earlier “self”? To answer some of these questions, I proposed

the Danger model, which suggests that the immune system is more concerned with damage than with foreignness, and is called

into action by alarm signals from injured tissues, rather than by the recognition of nonself”

Now at dis d query arise

\\

Why do mammal attack their newly growing sperm if their blood testis barrier break [mumps inducedOrchitis] ?

another query

Experiment-1 :- If breast milk from a lady is subcutaneous injected into a second lady , then there is immune reaction in second lady.

Experiment-2 :-- But upon sc injection of her own milk in 1st lady , there is no immune reaction.

But if SNS model is wrong , and as milk [of 1st lady ] is causing no danger in 2nd lady…… so immune reaction in 2nd lady against milk of 1st lady should have never occurred.

[ Fact that milk protein is actually not a danger molecule in human body is proved from experiment-2 above]

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